Režisieriai
- Paul W. S. Anderson
Prodiuseriai
- Jeremy Bolt
- Hiroyuki Kobayashi
- Paul W. S. Anderson
- Don Carmody
- Robert Kulzer
- Bernd Eichinger
- Samuel Hadida
Aktoriai

Milla Jovovich
Alice

Wentworth Miller
Chris Redfield

Ali Larter
Claire Redfield

Kim Coates
Bennett

Kacey Clarke
Crystal

Shawn Roberts
Albert Wesker

Sergio Peris-Mencheta
Angel

Boris Kodjoe
Luther West

Spencer Locke
K-Mart

Sienna Guillory
Jill Valentine

Norman Yeung
Kim Yong

Ray Olubowale
Axeman

Christopher Kano
Sniper

Tatsuya Goke
Sniper

Fulvio Cecere
Wendell

Nobuya Shimamoto
Technician #1

Denis Akiyama
Captain Hotaka

Kenta William Tomeoki
Technician #2

Peter Kosaka
Duty Officer

Shin Kawai
Umbrella Sergeant

Mika Nakashima
J Pop Girl

Takato Yamashita
Business Man

Hiromi Okuyama
Kogel Girl Undead

Iain Glen
Dr. Isaacs (archive footage)

Bill Blair
Featured Zombie (uncredited)

Emmanuel Buriez
Zombie (uncredited)

Martin Crewes
Chad Kaplan (uncredited)

Jamie Ferenczi
Survivor (uncredited)

Stefen Hayes
Yuri Loginova (uncredited)

Brian Jansen
Zombie (uncredited)

Azmyth Kaminski
Zombie (uncredited)

Devon Richards
Zombie (uncredited)

Jay Yoo
Japanese soldier (uncredited)