Režisieriai
- Lana Wachowski
- Lilly Wachowski
- Tom Tykwer
Scenaristai
- Lilly Wachowski
- Lana Wachowski
- Tom Tykwer
Prodiuseriai
- Tom Tykwer
- Lilly Wachowski
- Lana Wachowski
- Stefan Arndt
- Grant Hill
- Alexander Rodnyansky
Aktoriai

Tom Hanks
Dr. Henry Goose / Hotel Manager / Isaac Sachs / Dermot Hoggins / Cavendish Look-a-Like Actor / Zachry

Halle Berry
Native Woman / Jocasta Ayrs / Luisa Rey / Indian Party Guest / Ovid / Meronym

Jim Broadbent
Captain Molyneux / Vyvyan Ayrs / Timothy Cavendish / Korean Musician / Prescient 2

Hugo Weaving
Haskell Moore / Tadeusz Kesselring / Bill Smoke / Nurse Noakes / Boardman Mephi / Old Georgie

Jim Sturgess
Adam Ewing / Poor Hotel Guest / Megan's Dad / Highlander / Hae-Joo Chang / Adam / Zachry Brother-in-Law

Bae Doona
Tilda / Megan's Mom / Mexican Woman / Sonmi-451 / Sonmi-351 / Sonmi Prostitute

Ben Whishaw
Cabin Boy / Robert Frobisher / Store Clerk / Georgette / Tribesman

James D'Arcy
Young Rufus Sixsmith / Old Rufus Sixsmith / Nurse James / Archivist

Zhou Xun
Talbot / Hotel Manager / Yoona-939 / Rose

Keith David
Kupaka / Joe Napier / An-kor Apis / Prescient

Susan Sarandon
Madame Horrox / Older Ursula / Yusouf Suleiman / Abbess

Hugh Grant
Rev. Giles Horrox / Hotel Heavy / Lloyd Hooks / Denholme Cavendish / Seer Rhee / Kona Chief

David Gyasi
Autua / Lester Rey / Duophsyte

Robert Fyfe
Old Salty Dog / Mr. Meeks / Prescient 1

Martin Wuttke
Mr. Boerhaave / Guard / Leary the Healer

Robin Morrissey
Young Cavendish

Brody Nicholas Lee
Javier Gomez / Jonas / Zachry's Older Nephew

Ian van Temperley
Enforcer

Amanda Walker
Veronica

Ralph Riach
Ernie

Andrew Havill
Mr. Hotchkiss

Tanja de Wendt
Mrs. Hotchkiss

Raevan Lee Hanan
Little Girl with Orison at Papa Song's / Catkin / Zachry Relative

Götz Otto
Groundsman Withers

Niall Greig Fulton
Haskell Moore's Dinner Guest / Mozza Hoggins

Louis Dempsey
Haskell Moore's Dinner Guest / Jarvis Hoggins

Martin Docherty
Haskell Moore's Dinner Guest / Eddie Hoggins

Alistair Petrie
Haskell Moore's Dinner Guest / Musician / Felix Finch / Lascivious Businessman

Zhu Zhu
Megan Sixsmith / 12th Star Clone

Sylvestra Le Touzel
Haskell Moore's Dinner Guest / Nurse Judd / Aide in Slaughtership

Jojo Schöning
Papa Song Punk

Laura Vietzen
Young Ursula

Thomas Kügel
Vater

Marie Rönnebeck
Ursula's Daughter

Ruby Kastner
Young Girl

Emma Werz
Ursula's Granddaughter

Mya-Lecia Naylor
Miro

Korbyn Hawk Hanan
Adam Grandson

Katy Karrenbauer
Axwoman

Dulcie Smart
Ursula's Mother / Herbalist

Anna Holmes
Scientist / Executive

Shaun Lawton
Secretary

Moritz Berg
Porter

Gigi Lee
Zachry Relative

Genevien Lee
Zachry Relative

Cody Benjamin Lee
Zachry Relative

Heike Hanold-Lynch
Ms. Judd Look-a-like

Victor Solé
Mr. Roderick

Kristoffer Fuss
Lead Enforcer

Marco Albrecht
Scan Enforcer

Gary McCormack
Crane Operator

David Mitchell
Union Spy